Debugging switches may be specified for each supported language. Does your script accept command-line parameters? ASE makes it easy by providing an editable drop-down list on the toolbar alongside the execute and debug buttons so you can easily add command line parameters to execute from within ASE, and may just as easily recall other sets of command line parameters.

This first toolbar button launches the script, the second launches it with any specified debug switches (languages must support a debug switch). Finally, for testing purposes, this last area provides a place where you may easily specify any switches required by your script.
You may dictate what switches are passed to the command interpreter for both normal execution and for debugging in the Languages tab in the Options dialog.
For VBScript code debugging, you must have an installed script debugger. You may obtain the free Microsoft Script Debugger here. Note that you may need to restart your system following installation of your debugger in order for it to be recognized by ASE.